李博(表面)

职 称:

所在系所:表面室

个人主页:http://gr.xjtu.edu.cn/web/libo1137

E-MAIL:libo1137@xjtu.edu.cn

专业方向:医用金属表面改性

研究领域或方向

l 医用金属(镁、钛)表面活化改性及其生物学调控机制研究

l 3D打印多孔金属及其生物学性能研究

l 医用金属表面抗菌涂层制备及其抗菌机理研究

工作经历

l 2019.7-至今 新葡萄8883官网AMG材料科学与工程学院 副教授

l 2016.4-2019.6 新葡萄8883官网AMG材料科学与工程学院  讲师

l 2016.4-至今 新葡萄8883官网AMG生命学院 博士后

科研项目

l 国家自然科学基金青年项目(31700860,2018.01-2020.12, 主持

l 中国博士后面上项目(2017M613128),2017.09-2019.09,主持

l 新葡萄8883官网AMG新教师支持计划

l 国家自然科学基金重点项目(51631007),2017.01-2021.12,参加

学术成果

l Y. Jing#, Bo Li#, M. Li, Y.F. Zheng, S.L. Wu, Y. Han*, ROS induced bactericidal activity of amorphous Zn-doped titanium oxide coatings and enhanced osseointegration in bacteria-infected rat tibias, Acta Biomaterialia, published on line 2020, DOI: 10.1016/j.actbio.2020.02.036

l B. Li, P. Gao, H.Q. Zhang, Z. Guo, Y.F. Zheng, Y. Han*, Osteoimmunomodulation, osseointegration, and in vivo mechanical integrity of pure Mg coated with HA nanorod/pore-sealed MgO bilayer, Biomaterials Science, 2018 6: 3202-3218

l Bo Li, Yong Han*, Mei Li. Enhanced osteoblast differentiation and osseointegration of bio-inspired HA nanorod patterned pore-sealed MgO bilayer coating on magnesium, Journal of materials chemistry B, 2016, 4: 683-693

l Bo Li, Yong Han*, Kai Qi. Formation mechanism, degradation behavior, and cytocompatibility of a nanorod-shaped HA and pore-sealed MgO belayer coating on magnesium, ACS applied materials & interfaces, 2014, 6: 18258-18274

l Bo Li , Yong Han*. Fast formation of a novel bilayer coating with enhanced corrosion resistance andcytocompatibility on magnesium, RSC Advances, 2015, 5: 46109-46118

l J.H. Zhou#, L.Z. Zhao#, B. Li, Y. Han*, Nanorod diameter modulated osteogenic activity of hierarchical micropore/nanorod-patterned coatings via a Wnt/β-catenin pathway, Nanomedicine: Nanotechnology, Biology, and Medicine, 14 (2018) 1719-1731

l J.H. Zhou, B. Li, Y. Han*, F-doped TiO2 microporous coating on titanium with enhanced antibacterial and osteogenic activities, Scientific reports, 8 (2018) 17858

l Y.N. ZhanL. ZhangB. Li, Y. Han*, Enhancement in sustained release of antimicrobial peptide from dual-diameter-structured TiO2 nanotubes for long-lasting antibacterial activity and cytocompatibility, ACS Applied Materials & Interfaces, 9 (2017) 9449-9461

l J.H. Zhou, B. Li, L.Z Zhao, L. Zhang, Y. Han*, F-doped micropore/nanorod hierarchicallypatterned coatings for improving antibacterial and osteogenic activities of bone implants in bacteria-infected cases, ACS Biomaterials Science & Engineering, 2016 3: 1437-1450

l Jianhong Zhou, Bo Li, Yong Han*, Lingzhou Zhao*, The Osteogenic Capacity of Biomimetic Hierarchical Micropore/nanorod-patterned Sr-HA Coatings with Different Interrod Spacings, Nanomedicine: Nanotechnology, Biology, and Medicine, 2016, 12(5): 1161-1173

l Jianhong Zhou, Bo Li, Shemin Lu, Lan Zhang, Yong Han*, Regulation of Osteoblast Proliferation and Differentiation by Interrod Spacing of Sr-HA Nanorods on Microporous Titania Coatings, ACS applied materials & interfaces, 2013, 5(11): 5358-5365

l 授权专利:憨勇,李博,镁基表面致密氧化镁/羟基磷灰石纳米纤维双层涂层的制备工艺,2015.03.24,中国,201210366536.1

l 授权专利:李博,秦亮,憨勇, 镁基表面具有自愈合功能的活性涂层及其制备方法, 2020-04-02,中国,201910217929.2.